Introduction: Many children in Nigeria have sickle cell anemia, more than any other country. These children are oftentimes more likely to have a stroke. A stroke can happen because of low blood count, swollen blood vessels, heart problems, and trouble with blood...
Objective: To see if administration of long-term transfusion (transfer of healthy red blood cells) in children with sickle cell anemia can improve growth.Study design: In the Stroke Prevention Trial for Sickle Cell Anemia Study, patients were randomly put in two...
The Post-STOP study looked at how often bleeding in the brain, called hemorrhagic strokes, occurs in children and young adults with sickle cell anemia. Sickle cell anemia is a condition where the red blood cells, normally round, are shaped abnormally (sickle shape)....
Sickle cell anemia (SCA) is an inherited disease where red blood cells change shape and become sickle-shaped instead of round. Since this can clog and damage blood vessels, it also increases the risk of stroke. In wealthier countries, children with SCA who face a high...
Sickle cell disease is a genetic condition that causes red blood cells to stick together leading to infections and episodes of pain and difficulty breathing. Around 8% of children with sickle cell disease will have a stroke. An important study, The Stroke Prevention...
The Stroke Prevention Trial in Sickle Cell Anemia (STOP) was a research study aiming to see if regular blood could help stop the first stroke in children with sickle-cell anemia who were at high risk. They used a technique called transcranial Doppler (TCD) to identify...
Sickle cell anemia is an inherited blood problem where your red blood cells, which are usually round and flexible, change into a shape like a crescent or sickle. These odd-shaped cells can get stuck in the tiny pathways in our body, called blood vessels, which can...